Table 2.

Sensitivity and specificity for detecting acute hepatitis, chronic hepatitis, and nonspecific reactive hepatitis in clinically healthy Labrador retrievers

	Sensitivity (95% CI)	Specificity (95% CI)	AUC (95% CI)
Acute hepatitis
ALT 70 U/L	0.45 (0.25–0.65)	0.93 (0.85–0.99)	0.82 (0.69–0.94)
ALP 89 U/L	0.15 (0.00–0.35)	0.99 (0.96–1.00)	0.66 (0.53–0.79)
BA 10 μmol/L	0.15 (0.00–0.30)	0.90 (0.83–0.97)	0.58 (0.43–0.72)
Chronic hepatitis
ALT 70 U/L	0.71 (0.47–0.94)	0.93 (0.85–0.99)	0.94 (0.87–1.00)
ALP 89 U/L	0.35 (0.12–0.59)	0.99 (0.96–1.00)	0.76 (0.63–0.89)
BA 10 μmol/L	0.13 (0.00–0.31)	0.90 (0.81–0.96)	0.55 (0.39–0.71)
Nonspecific reactive hepatitis
ALT 70 U/L	0.05 (0.01–0.09)	0.93 (0.85–0.99)	0.61 (0.52–0.70)
ALP 89 U/L	0.02 (0.00–0.06)	0.99 (0.96–1.00)	0.59 (0.50–0.68)
BA 10 μmol/L	0.04 (0–0.08)	0.90 (0.83–0.97)	0.43 (0.34–0.52)

ALT, alanine aminotransferase; ALP, alkaline phosphatase; AUC, area under the curve; BA, bile acids; CI, confidence interval.