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Effect of Janus kinase (JAK) inhibition on phosphorylated signal transducer and activator of transcription (STAT) phosphorylation in RA neutrophils. Freshly isolated (0 h) RA neutrophils exhibited elevated levels of STAT‐1 and STAT‐3, which decreased during 60 min incubation in untreated conditions. Addition of baricitinib and tofacitinib (200 ng/ml) at 0 h induced a loss of phosphorylated STAT‐1 and STAT‐3 compared to untreated cells at 30 and 60 min.
