Table 3.
Metabolic variables (median [range]) in obese and ideal weight patient groups
| Obese Dogs | Ideal Weight Dogs | P | |
|---|---|---|---|
| Insulin:Glucosea | 44.4 (11.5–220.6) | 20.0 (8.8–42.2) | <0.001 |
| Insulin (μU/mL) | 45.9 (11.5–207.3) | 18.7 (8.6–34.3) | <0.001 |
| Glucose (mg/dL) | 97 (72–135) | 93 (74–128) | 0.616 |
| Lipid panel | |||
| Adiponectin (μg/mL) | 15.9 (1.9–54.7) | 25.5 (10.5–50.1) | 0.021 |
| Cholesterol (mg/dL) | 259 (107–482) | 214 (143–292) | 0.005 |
| Triglycerides (mg/dL) | 108 (41–2171) | 55 (32–229) | 0.003 |
| HDL (mg/dL) | 169 (81–248) | 151 (109–195) | 0.012 |
| LDL (mg/dL) | 49 (0–157) | 46 (18–93) | 0.679 |
| Inflammatory markers | |||
| IL‐8 (pg/mL) | 7280 (548–145656) | 2468 (6.1–10747) | 0.011 |
| KC like (pg/mL) | 2226 (327–5430) | 873 (211–4430) | 0.017 |
| GM‐CSF (pg/mL) | 6.1 (6.1–3709) | 6.1 (6.1–866) | 0.615 |
| INF‐gamma (pg/mL) | 1.22 (1.22–25.91) | 1.22 (1.22–2025) | 0.199 |
| IL‐2 (pg/mL) | 6.1 (6.1–5308) | 6.1 (6.1–828) | 0.389 |
| IL‐6 (pg/mL) | 12.3 (6.1–3685) | 21.6 (6.1–486) | 0.576 |
| IL‐7 (pg/mL) | 6.1 (6.1–6017) | 6.1 (6.1–1053) | 0.648 |
| IP 10 (pg/mL) | 6.1 (6.1–125) | 6.1 (6.1–588) | 0.206 |
| IL‐10 (pg/mL) | 6.1 (6.1–18113) | 11.1 (6.1–97.2) | 0.517 |
| MCP‐1 (pg/mL) | 259 (6.1–1048) | 296 (6.1–524) | 1 |
| TNF‐alpha (pg/mL) | 6.1 (6.1–1356) | 6.1 (6.1–221) | 0.528 |
HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; GM‐CSF, granulocyte‐macrophage colony‐stimulating factor; IL, interleukin; TNF‐alpha, tumor necrosis factor‐alpha; INF, interferon; TNF, tumor necrosis factor; MCP, monocyte chemoattractant protein; IP, interferon gamma‐induced protein; KC, keratinocyte‐derived chemokine; P: P‐values derived from Mann‐Whitney tests.
a
Primary outcome.