Table 2.
Characteristics, clinical aspects, and outcome in dogs with chronic diarrhea
| Disease Group | Characteristics | Clinical aspects | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | Sex | Age | Weight/Breed size | Body condition | N | CIBDAI | Localization | Outcome | |||||||||
| In years | Group | Weight in kg | Size | Score (1–5 points) | Group | Score (1–18 points) | Group | Group | Group | ||||||||
| M/MN/F/FN | Median | Range | YO/MA/OL | Median | Range | SM/ME/LA | Median | Range | T/U/I/O/A | Median | Range | IN/MI/MO/SV | SI/LI/DI | CR/PR/NR | |||
| Total | 136 | 60/19/33/24 | 5.5 | 0.5–15.0 | 30/69/37 | 20.1 | 2.0–70.5 | 31/42/63 | 2 | 1–5 | 17/66/46/6/1 | 127 | 7 | 2–16 | 5/24/54/44 | 42/36/49 | 68/43/16 |
| PE vs. SE (P valuea) | .488 | .113 | .688 | .066 | .190 | .454 | .962 | .501 | .315 | .001 | 1.000 | ||||||
| PE | 123 | 53/17/32/21 | 5.0 | 0.5–13.5 | 28/63/32 | 21.8 | 2.0–70.5 | 27/36/60 | 2 | 1–5 | 15/59/42/6/1 | 116 | 7 | 2–16 | 5/24/47/40 | 33/36/47 | 62/39/15 |
| SE | 13 | 7/2/1/3 | 8.0 | 1.0–15.0 | 2/6/5 | 9.5 | 2.0–32.0 | 4/6/3 | 2 | 1–3 | 2/7/4/0/0 | 11 | 7 | 6–12 | 0/0/7/4 | 9/0/2 | 6/4/1 |
| Selected diagnoses with PE (P valuea) | .328 | <.001 | .006 | .462 | .076 | .008 | .155 | <.001 | <.001 | .071 | <.001 | ||||||
| FRE | 64 | 28/7/16/13 | 5.3a | 0.5–13.5 | 13/36/15 | 17.3 | 3.1–51.3 | 15/25/24 | 2 | 1–5 | 4/29/26/4/1 | 61 | 7a | 2–14 | 5/14/30/12 | 17/20/24 | 40/21/0 |
| ARE | 11 | 5/2/4/0 | 4.0a,b | 1.0–12.0 | 2/7/2 | 26.0 | 3.8–68.5 | 4/1/6 | 2 | 2–4 | 0/7/3/1/0 | 10 | 7a,b | 4–13 | 0/3/5/4 | 1/4/5 | 6/4/0 |
| IBD | 22 | 8/3/5/6 | 8.0a | 1.0–12.5 | 4/8/10 | 28.8 | 2.0–70.5 | 6/2/14 | 2 | 1–3 | 6/11/5/0/0 | 21 | 10b | 4–16 | 0/1/5/15 | 8/1/12 | 4/10/7 |
| LYM | 5 | 2/2/0/1 | 9.0a | 7.0–13.0 | 0/2/3 | 30.0 | 24.0–35.0 | 0/1/4 | 2 | 1–2 | 2/3/0/0/0 | 5 | 11a,b | 5–15 | 0/1/0/4 | 3/1/1 | 0/0/5 |
| Giardia | 15 | 7/2/6/0 | 1.5b | 0.5–6.5 | 9/6/0 | 22.0 | 2.4–40.5 | 2/5/8 | 3 | 1–4 | 1/6/7/1/0 | 13 | 6a | 4–12 | 0/4/8/1 | 3/7/3 | 9/4/0 |
| Selected diagnoses with SEb | |||||||||||||||||
| EPI | 4 | 3/0/1/0 | 5.5 | 1.0–14.0 | 1/2/1 | 16.5 | 5.7–27.0 | 2/0/2 | 2 | 1–2 | 2/2/0/0/0 | 4 | 7 | 6–12 | 0/0/3/1 | 4/0/0 | 3/1/0 |
| CP | 3 | 0/0/0/3 | 10.0 | 6.5–11.0 | 0/1/2 | 20.1 | 4.6–32.0 | 1/1/1 | 3 | 2–3 | 0/1/2/0/0 | 3 | 10 | 9–12 | 0/0/0/3 | 2/0/1 | 2/1/0 |
| Outcome (P valuea) | .858 | .018 | .081 | <.001 | .010 | .132 | .541 | .005 | .056 | .241 | |||||||
| CR | 68 | 32/10/16/10 | 4.5a | 0.5–14.0 | 20/32/16 | 17.0a | 2.0–47.0 | 20/24/24 | 2 | 1–4 | 7/32/25/4/0 | 68 | 7a | 3–15 | 3/15/31/19 | 21/22/25 | |
| PR | 43 | 17/5/12/9 | 5.5a | 0.5–13.5 | 7/26/10 | 22.5a,b | 2.0–68.5 | 7/14/22 | 2 | 1–5 | 5/20/15/2/1 | 43 | 7a | 2–16 | 2/8/20/13 | 12/12/19 | |
| NR | 16 | 6/3/3/4 | 8.8b | 1.0–13.0 | 1/7/8 | 30.1b | 13.0–70.5 | 0/3/13 | 2 | 1–3 | 5/7/4/0/0 | 16 | 11b | 5–15 | 0/1/3/12 | 9/2/5 | |
P values based on Pearson chi‐square or Fisher's exact tests to compare categorical variables and Kruskal‐Wallis comparison of differences among medians. Medians without superscripts in common are statistically different based on Mann‐Whitney U‐tests and Bonferroni adjustment for multiple comparisons. Significance < .05.
Data for selected diagnoses with a group size of 3 or 4 dogs were descriptively analyzed. M, male; MN, male neutered; F, female; FN, female spayed; YO, young (less 2 years); MA, middle‐aged (≥2 to <9 years); OL, old (9 years and older); SM, small‐size breed; ME, medium‐size breed; LA, large‐size breed; T, thin; U, underweight; I, ideal weight; O, overweight; A, adipous; CIBDAI, canine inflammatory bowel disease activity index; IN, clinically insignificant disease; MI, mild disease; MO, moderate disease; SV, severe disease; SI, small intestinal disease; LI, large intestinal disease; DI, diffuse intestinal disease; CR, complete recovery; PR, partial recovery; NR, no recovery; PE, primary enteropathy; SE, secondary enteropathy; FRE, food responsive enteropathy; ARE, antibiotic responsive enteropathy; IBD, idiopathic inflammatory bowel disease; LYM, intestinal lymphoma; Giardia, infection with Giardia spp.; EPI, exocrine pancreatic insufficiency; CP, chronic pancreatitis.