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Group differences in cortical bone properties (femur mid-shaft). Delayed insulin therapy via osmotic minipumps (CSII) rescued the T1D-induced loss in cortical cross-sectional area but not the loss in the moment of inertia. Even though the bone structure was not fully restored, delayed CSII partially improved whole-bone stiffness and strength. a: adjusted p-value < 0.05 vs. ND-Veh and b: adjusted p-value < 0.05 vs. T1D-Veh.
