TABLE 1.
IMRT | % | Conventional | % | Total | ||
---|---|---|---|---|---|---|
Number of patients | 48 | 282 | 330 | |||
Median follow-up surviving (months) | 44 | 66 | 59 | |||
Time Period | P < .001 | |||||
1989-1995 | 0 | 0% | 59 | 20.9% | 59 | |
1996-2005 | 0 | 0% | 169 | 59.9% | 169 | |
2006-2011 | 48 | 100% | 54 | 19.1% | 102 | |
Age | P = .237 | |||||
Median (years) | 65 | 68 | 68 | |||
≤65 | 25 | 52.1% | 121 | 42.9% | 146 | |
>65 | 23 | 47.9% | 161 | 57.1% | 184 | |
Gender | P = .028 | |||||
Male | 37 | 77.1% | 250 | 88.7% | 287 | |
Female | 11 | 22.9% | 32 | 11.3% | 43 | |
T-stage | P = .462 | |||||
Tis | 3 | 6.3% | 13 | 4.6% | 16 | |
T1 | 32 | 66.7% | 212 | 75.2% | 244 | |
T2 | 13 | 27.1% | 57 | 20.2% | 70 | |
T2 Subcategories | ||||||
Supraglottic extension | 6 | 12.5% | 14 | 5.0% | 20 | |
Subglottic extension Impaired Cord | 4 | 8.3% | 31 | 11.0% | 35 | |
Mobility | 3 | 6.3% | 12 | 4.3% | 15 | |
Radiation dose | P < .001 | |||||
Median dose (Gy) | 63 | 66 | 66 | |||
65.25 Gy or less | 47 | 97.9% | 85 | 30.1% | 132 | |
66 Gy or more | 1 | 2.1% | 197 | 69.9% | 198 | |
Fraction size | P < .001 | |||||
200 cGy or less | 0 | 0.0% | 206 | 73.0% | 206 | |
225 cGy | 48 | 100.0% | 77 | 27.3% | 125 | |
Smoking | P = .603 | |||||
Yes | 43 | 89.6% | 245 | 86.9% | 288 | |
No | 5 | 10.4% | 37 | 13.1% | 42 |
Abbreviation: Gy, Gray; IMRT, intensity-modulated radiotherapy.