TABLE 3.

Cox proportional hazards univariate analysis of local control, laryngectomy-free survival (LFS), distant metastasis, and overall survival in T1-2N0 glottic carcinoma.

Univariate Analysis	Local Control		LFS		Distant Metastasis		Overall Survival
	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value	HR (95% CI)	p Value
IMRT vs Conventional	0.96 (0.38-2.47)	0.938	1.39 (0.73-2.65)	0.318	2.47 (0.48-12.65)	0.278	1.85 (0.89-3.86)	.100
T2 vs. T1 stage	2.38 (1.26-4.49)	0.008	1.81 (1.16-2.83)	0.009	3.57 (0.88-14.40)	0.076	1.37 (0.83-2.25)	.215
Age	1.00 (0.97-1.02)	0.874	1.04 (1.01-1.05)	<0.001	1.07 (0.99-1.14)	0.068	1.07 (1.04-1.09)	<.001
Smoking (yes vs no)	0.45 (0.22-0.91)	0.027	1.19 (0.64-2.22)	0.583	0.48 (0.10-2.37)	0.365	1.80 (0.83-3.92)	.138
Gender (Male vs female)	1.18 (0.46-3.01)	0.729	1.14 (0.65-2.00)	0.649	0.51 (0.10-2.54)	0.409	1.01 (0.55-1.86)	.977
Fractionation (2.25 vs 2 Gy)	1.03 (0.54-1.96)	0.925	1.077 (0.684-1.696)	0.748	1.32 (0.30-5.77)	0.710	1.31 (0.78-2.22)	.312
Total dose	1.00 (0.999-1.001)	0.796	1.00 (1.000-1.001)	0.690	1.00 (0.998-1.004)	0.377	1.00 (0.999-1.001)	.836
Year of treatment	1.00 (0.95-1.06)	0.973	1.01 (0.97-1.05)	0.720	1.08 (0.93-1.26)	0.291	1.01 (0.97-1.06)	.605

Abbreviations: CI, confidence interval; HR, hazard ratio.