Figure 3.
fen1-1 is hypersensitive to methyl methanesulfonate (MMS).
Phenotype of 2-week-old seedlings on MS medium supplemented with different concentrations of DNA-damaging reagents: MMS (a); hydroxyurea (HU; c); and cis-diamineplatinum (II) dichloride (Cis; e). The fas1 mutant (Columbia-0 background) was used as a positive control. (b), (d), (f) Statistical analyses of the seedling fresh weight after treatment relative to no treatment as indicated in the left panel. Bars represent standard error from three biological replicates. *P < 0.05; **P < 0.01; ***P < 0.001, ns, not statistically significant; paired t-test. TWT, transgenic wild type.