Table 1.
Baseline Patient Characteristics.
| Characteristics | No C. difficile (n=672) | NonToxigenic C. difficile (n=97) | Toxigenic C. difficile (n=651) | P-value |
|---|---|---|---|---|
| Age, years (mean, SD) | 54.7 (18.6) | 55.7 (22.3) | 54.9 (23.2) | 0.903 |
| Female (n, %) | 364 (54.2%) | 51 (52.6%) | 357 (54.8%) | 0.907 |
| Non-White (n, %) | 115 (17.1%) | 16 (16.5%) | 130 (20.0%) | 0.360 |
| Inpatient at baseline (n, %) | 555 (82.6%) | 72 (74.2%) | 400 (61.4%) | <0.001 |
| Nursing home (n, %) | 7 (1.0%) | 7 (7.2%) | 78 (12.0%) | <0.001 |
| Charlson Deyo Score (mean, SD) | 1.37 (1.60) | 1.32 (1.49) | 1.28 (1.53) | 0.581 |
| Antibiotics during past 2 weeks (n, %) | 425 (62.2%) | 54 (54.5%) | 359 (50.6%) | <0.001 |
| Proton pump inhibitors during past 2 weeks (n, %) | 323 (47.3%) | 47 (47.5%) | 228 (32.1%) | <0.001 |
| H2 receptor antagonists during past 2 weeks (n, %) | 132 (19.3%) | 19 (19.2%) | 115 (16.2%) | 0.292 |
| Number admissions during previous 28 days: | ||||
| 0 | 577 (85.9%) | 80 (82.5%) | 552 (84.8%) | |
| 1 | 86 (12.8%) | 14 (14.4%) | 91 (14.0%) | |
| 2+ | 9 (1.3%) | 3 (3.1%) | 8 (1.2%) | 0.614 |
| Number nights in hospital during previous 180 days (mean, SD) | 12.6 (16.2) | 13.6 (17.9) | 10.6 (16.7) | 0.042 |
| Number prior positive C. difficile tests: | ||||
| 0 | 636 (94.6%) | 80 (82.5%) | 531 (81.6%) | |
| 1 | 29 (4.3%) | 13 (13.4%) | 97 (14.9%) | |
| 2+ | 7 (1.0%) | 4 (4.1%) | 23 (3.5%) | <0.001 |