Fig. 1. (A) Agarose gel with RCA products under different conditions: the DNA walking biosensor with only one walker, C1, incubated in the presence of let-7a (lane a); the DNA walking biosensor with two walkers, C1 and C2, incubated in the presence of let-7a (lane b) and in the absence of let-7a (lane c), and marker (lane d). (B) The fluorescence responses of the walking biosensor to 10 nM let-7a with background in the presence of the two walkers C1 and C2 (curve a and c), and in the presence of only walker C1 (curve b and d).
