Table 2.
Baseline characteristics of patients with either severe sepsis or septic shock treated in the ED with our bundled care initiative
| ED directly to ICU | ED towards (including delayed ICU transfers within 48 h) | p value | |
|---|---|---|---|
| Number | 556 | 358 | |
| Age, years | 58.8 (±18) | 58.4 (±18) | 0.785 |
| Sex, %male (n) | 57.6% (320) | 55.3% (198) | 0.337 |
| Triage SBP (mm Hg) | 105 (±28) | 112 (±28) | 0.001 |
| Shock index (SBP/HR) | 1.11 (±0.33) | 1.02 (±0.30) | 0.002 |
| Triage HR (BPM) | 111 (±29) | 110 (±23) | 0.662 |
| Fluids per kg within 6 h of presentation | 40.1 (±20.7) | 33.2 (±18.9) | <0.005 |
| Initial lactate (mmol/L) | 4.1 ± 3.4 | 2.8 ± 2.3 | <0.005 |
| % with septic shock at presentation (n) | 55.6% (310) | 0% (0) | <0.005 |
| Site of infection%, (n) | <0.005 | ||
| Abdominal | 14.9% (83) | 17.6% (63) | |
| Cardiac | 1.3% (7) | 1.1% (4) | |
| Central nervous system | 1.1% (6) | 1.4% (5) | |
| Genitourinary | 21.9% (122) | 31.3% (112) | |
| Musculoskeletal | 7.0% (39) | 13.4% (48) | |
| Pulmonary | 24.8% (138) | 22.3% (80) | |
| Unknown/othersa | 28.9% (161) | 12.9% (46) | |
| Mortality,% (n) | 24.6% (137) | 12.0% (43) | <0.005 |
aOthers include patients with multiple organ system infections, catheter-related infections, head and neck infection, and neutropenic fever without definitive source