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. Author manuscript; available in PMC: 2018 May 4.
Published in final edited form as: Mol Cell. 2017 May 4;66(3):384–397.e8. doi: 10.1016/j.molcel.2017.04.012

Figure 1. H1 stabilises a compact nucleosome conformation.

Figure 1

(A,B) Gallery of class averages of 197-bp 601 nucleosomes in the (A) absence and (B) presence of histone H1.0. (C) Close-up views. (D) Representative 3D classes showing different linker DNA orientations in the unbound state (3 of 8 conformational classes are shown) or bound to H1.0 or H1.5ΔC50 (all 3 classes are shown). (E) Distribution of linker DNA exit angles in the unbound state (black) or bound to H1.0 (magenta) or H1.5ΔC50 (green). See also Figure S1.