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. Author manuscript; available in PMC: 2018 Jun 9.
Published in final edited form as: Circ Res. 2017 May 10;120(12):1947–1957. doi: 10.1161/CIRCRESAHA.116.309947

Figure 1. Differences in Cardiac Functional Parameters (Measured by cardiac MRI) at baseline and 6 month follow-up Versus Peripheral Blood Concentrations of Interleukin 6 and Interleukin 10.

Figure 1

The differences of cardiac MRI (A) ejection fraction (EF), (B) left ventricular end systolic volume (LVESV) and (C) left ventricular end diastolic volume (LVEDV) at baseline immediately prior to cell therapy and six months follow up are plotted according to peripheral blood IL-6 and IL-10 levels. Participants with high IL-6 and IL-10 concentration in PB (IL-6 hi IL-10 hi ) showed significantly lower LVEF changes at 6 months follow up (-3.41 ± 5.3 vs. 13.84 ± 7.8, P=0.01). Moreover study participants with IL-6 hi IL-10 hi showed an increase in LVESV (+14.6 mL ± 25.3 mL) at 6 months follow up compared with those with IL-6 hi IL-10 lo (-52.4 mL ± 63.19 mL, P=0.03). (* P<0.05).