Table 1.
Summary of the main clinical, ophthalmic, hearing, and radiologic findings
| Findings | Twin 1 | Twin 2 |
|---|---|---|
| Clinical | ||
| Sex | Female | Female |
| Head circumference at birth (cm) | 26.0 | 28.5 |
| RT-PCR or Zika virus-specific IgM | Negative | Negative |
| Ophthalmological | ||
| Exotropia | Yes | Yes |
| Nystagmus | Yes | No |
| Focal pigment mottling | No | No |
| Uveitis | No | No |
| Retina and optic nerve abnormalities | No | No |
| Hearing screening | ||
| Hearing loss | Yes | No |
| Transfontanellar ultrasonography | ||
| Subependymal hemorrhage | Yes | Yes |
| Multiple punctiform calcifications | Yes | Yes |
| Reduced corpus callosum and cerebral parenchyma, and cortical thickness | Yes | Yes |
| Enlargement of atria and occipital horns of the lateral ventricles | Yes | No |
| Enlargement of the subarachnoid space | No | Yes |
RT-PCR = reverse transcription polymerase chain reaction.