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. 2016 Oct 31;13:19. doi: 10.1186/s12987-016-0040-3

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 18 — A second possible scheme for ion transport by the blood–brain barrier. This differs from the first, shown in Fig. 17, by swapping the positions of NBCe1 and AE2. For the key to lines and colours see the legend to Fig. 17. The consequences of the swap are considered in Sects. 4.6.1, 4.6.2