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. Author manuscript; available in PMC: 2018 Feb 3.
Published in final edited form as: ChemMedChem. 2017 Jan 18;12(3):250–256. doi: 10.1002/cmdc.201600538

Figure 4. FCBL activity on cancer cell mitochondria.

Figure 4

(a) FCBL and CBL induced DNA damage in the nuclear genome and mitochondrial genome. (b) The depolarizing effect of FCBL, F, CBL and F+CBL on MMP after 24-h incubation. (c) The effect of FCBL, F, CBL and the mixture of equivalent F and CBL, i.e., F+CBL, on ROS levels of mitochondria after 1.5-h incubation. Mean values plotted, n = 3, error bars equal SEM. Student’s two-tailed - t test was used to determine p values. ** indicates p value < 0.01.