Table 1.
Summary of IC50 values (μM, 24 h) in a panel of cell lines.
| Cell source | Cell line | CBL | F | CBL+F | FCBL |
|---|---|---|---|---|---|
| Human T cell lymphoblast-like cell | CCRF-CEM | 41.9 ± 5. 43 | 70.3 ± 6.78 | 32.7 ± 3.17 | 11.1 ± 1.97 |
| Human monocytic leukemia | U937 | 45.7 ± 3.71 | 66.8 ± 5.12 | 29.7 ± 3.86 | 10.3 ± 2.11 |
| Human multiple myeloma cell | MM.1S | 47.4 ± 5.08 | 63.3 ± 5.17 | 33.1 ± 4.16 | 12.1 ± 0.95 |
| Human multiple myeloma cell | MM.1R | 235.5 ± 16.88 | 66.7 ± 5.86 | 48.5 ± 3.99 | 13.5 ± 1.77 |
| Human chronic myeloid leukemia | K562 | 416.8 ± 27.88 | 89.2 ± 6.99 | 70.5 ± 6.37 | 11.3 ± 1.66 |
| Human chronic myeloid leukemia | K562/ADR | > 1000 ± 53.41 | 82.5 ± 7.31 | 65.4 ± 4.85 | 10.9 ± 1.74 |
| Human cervical cancer cell | HeLa | 320.7 ± 33.18 | 275.3 ± 20.78 | 159.5 ± 18.77 | 31.5 ± 3.57 |
| Human normal hepatoma cell | LO2 | > 600 ± 30.11 | > 900 ± 31.67 | > 600 ± 24.66 | > 900 ± 11.89 |
| Mouse embryonic fibroblasts cell | NIH3T3 | > 600 ± 17.66 | > 900 ± 20.19 | > 600 ± 16.47 | > 900 ± 22.15 |
Note: Cell survival was determined by MTT assays as described in Supporting Information. Data are mean ± SD of three independent experiments.