Table 3.
Frequently used antibodies detecting TBP protein in SCA17 animal models.
| Antibody | Epitope | Soluble form | Aggregates | Western blotting | Immunostaining |
|---|---|---|---|---|---|
| N-12 | N-terminus of human TBP | + | + | + | + |
| 1C2 | Expanded polyglutamine repeats | + | + | + | + |
| 1TBP18 | Amino acid residues 1–20 of TBP | + | + | + | + |
| EM192 | C-terminal of mouse TBP | + | + | + | − |
+ indicates the antibody works for that particular application; − indicates the antibody does not work for that particular application.