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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Diabetologia. 2017 May 20;60(8):1442–1453. doi: 10.1007/s00125-017-4303-6

Fig. 3.

Fig. 3

Effects of GLP-1 on beta cell lines. (a) Western blotting for insulin receptor (IR), IGF-1 receptor (IGF1R), GLP-1 receptor, EGF receptor and actin. (b) Western blotting for total and p-CREB and total and p-Akt normalised for actin 15 min after GLP-1 or insulin stimulation. (c) Western blotting for total and p-Akt 15 min after GLP-1 and/or insulin stimulation. (d) Western blotting for total and p-Akt 15 min after GLP-1 or insulin stimulation with or without 16 h nifedipine treatment. Representative images of three independent experiments are shown in all panels. Numbers below bands represent relative values of the density quantification. LoxLoxβ, beta cells from littermate insulin-receptor-floxed control mice