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. Author manuscript; available in PMC: 2017 Jul 13.
Published in final edited form as: Neuropsychopharmacology. 2006 Mar;31(3):594–601. doi: 10.1038/sj.npp.1300818

Table 1. Effects of Specific DAergic and NErgic Drugs on Pyramidal Cell Properties.

Treatment MP (mV) IR (MΩ) Number of spikes/pulse



Control Treatment Control Treatment Control Treatment
Control–MPH (10 μM, n = 30) 72.3 ± 0.2 72.2 ± 0.1 463.3 ± 47.8 435.0 ± 48 3.9 ± 0.3 5.1 ± 0.5*
Control–MPH (1 μM, n = 10) 71.3 ± 0.8 71.2 ± 0.4 359.2 ± 27.2 402.1 ± 37.8 2.8 ± 0.3 2.7 ± 0.6
Control–MPH (reserpine) 70.1 ± 0.6 69.4 ± 0.5 4.0 ± 0.7 4.3 ± 0.9
Control–prazosine–MPH 73.0 ± 0.1 73.5 ± 0.4 72.7 ± 0.2 445 ± 41.2 429.3 ± 40.3 405.4 ± 53.1 2.8 ± 0.2 3.9 ± 0.5 4.9 ± 0.9**
Control–yohimbine–MPH 72.9 ± 1.1 72.2 ± 1.9 72.3 ± 1.2 488.2 ± 82 439.8 ± 59.5 527.4 ± 60 3.4 ± 0.4 3.7 ± 0.5 3.2 ± 0.8
Control–propanolol–MPH 71.8 ± 2.5 71.8 ± 2.1 71.9 ± 2.0 423.4 ± 41.1 267 ± 92.9 420 ± 50.8 4.2 ± 0.8 5.2 ± 1.5 5.1 ± 1.4
Control–SKF 38390–MPH 72.3 ± 0.1 72.6 ± 0.2 71.9 ± 0.2 345.1 ± 64 232 ± 85 327 ± 81.1 3.1 ± 0.3 3.7 ± 0.7 5.4 ± 0.9***
Control–clonidine 71.8 ± 0.4 72.1 ± 0.3 575.3 ± 56.9 418.9 ± 62.7 3.4 ± 0.6 6.1 ± 0.7****

Bold values indicate significant changes.

*

p<0.0007.

**

p<0.01.

***

p<0.03.

****

p<0.000005.