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PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) diagram showing selection of included reviews. *The initial search results included studies on venom immunotherapy, which was subsequently determined to be outside the scope of this overview. Venom immunotherapy was assessed in the environmental scan portion of this drug class review (http://odprn.ca/wp-content/uploads/2016/02/Allergen-Immunotherapy_Environmental-Report_Oct-2-2015_FINAL.pdf).
