Figure 2.

Summary of benefits of subcutaneous (SCIT) and sublingual (SLIT) immunotherapy. The five contiguous circles correspond, respectively, to the 5 efficacy outcomes: total combined symptom-medication score, symptom score, medication score, disease-specific quality of life and adherence/discontinuation. A green circle indicates that immunotherapy is significantly better than placebo, a red circle indicates that immunotherapy is significantly worse than placebo, a grey circle indicates that there is no significant difference between immunotherapy and placebo, and a white circle indicates that the outcome was not available for analysis. In cases of immunotherapy versus immunotherapy, significance is reported relative to the first agent listed in the heading.