Table 3. Summary of all disease systems and subsets by reservoir category.
| Epidemic Potential Zone* | High Priority Zoonotic Pathogens† | ||||||
|---|---|---|---|---|---|---|---|
| Reservoir Category | All Systems (n = 330) | Dead-End (220) | Stuttering Chains (44) | Epidemic Potential (66) | Human Target (261) | Top 25% (109) | Top 10% (45) |
| Wildlife | 74.85% (247) | 76.36% (168) | 63.64% (28) | 77.27% (51) | 75.48% (197) | 74.31% (81) | 77.78% (35) |
| Domestic Animals | 41.52% (137) | 40.45% (89) | 54.55% (24) | 36.36% (24) | 41.76% (109) | 39.45% (43) | 33.33% (15) |
| Livestock | 24.24% (80) | 20.00% (44) | 43.18% (19) | 25.76% (17) | 23.75% (62) | 25.69% (28) | 28.89% (13) |
| Companion Animals | 20.00% (66) | 23.18% (51) | 15.91% (7) | 12.12% (8) | 21.46% (56) | 16.51% (18) | 4.44% (2) |
| Environment | 10.00% (33) | 13.18% (29) | 4.55% (2) | 3.03% (2) | 12.64% (33) | 6.42% (7) | 2.22% (1) |
Each reservoir was categorized by one or more of wildlife, domestic animals, livestock, companion animals, and environment. All domestic animal reservoir species were categorized as livestock, companion animals, or both, depending on which types of populations host the pathogen. Decisions between wildlife and/or livestock were made with the same criterion. The number of systems is given in parentheses.
*The epidemic potential zone subsets represent the transmission potential of the pathogen in the target host population(s) following spillover. The zones are defined as follows: dead-end for a basic reproductive number (R0) nearly equal to zero, stuttering chains for an R0 greater than zero but less than one, and epidemic potential for an R0 greater than one.
†High priority zoonotic pathogen subsets were determined by estimating the pathogen’s representation in the scientific literature using the H-index. Each subset was created to include pathogens that are among the 25% (Top 25%) and 10% (Top 10%) most significant known human pathogens.