Table 1. Patient and control demographic characteristics.
| Demographics | Mild / Moderate (N = 35) | Severe (N = 75) | P-Value |
| Age, years | 71 ± 10 | 78 ± 9 | <0.001 |
| Male, n (%) | 26 (74.3) | 51 (68.0) | 0.66 |
| Hypertension, n (%) | 13 (40.6) | 44 (58.7) | 0.096 |
| Diabetes mellitus, n (%) | 1 (3.8) | 4 (6.1) | 1.000 |
| Any coronary artery disease, n (%) | 13 (37.1) | 27 (36.0) | 1.00 |
| Previous stroke, n (%) | 1 (2.9) | 2 (2.7) | 1.00 |
| Atrial Fibrillation, n (%) | 5 (14.3) | 6 (8.0) | 0.32 |
| Hypercholesterolaemia, n (%) | 18 (58.1) | 50 (67.6) | 0.38 |
| NYHA ≥ II | 19 (59.4) | 60 (81.1) | 0.028 |
| Demographics | All Aortic Stenosis (N = 110) | Controls (N = 55) | P-Value |
| Age, years | 76 ± 10 | 74 ± 7 | 0.052 |
| Male, n (%) | 77 (70.0) | 39 (70.9) | 1.00 |
| Hypertension, n (%) | 57 (53.3) | 20 (36.4) | 0.047 |
| Diabetes mellitus, n (%) | 5 (5.4) | 10 (18.2) | 0.022 |
| Any coronary artery disease, n (%) | 40 (36.4) | 26 (47.3) | 0.18 |
| Previous stroke, n (%) | 3 (2.7) | 1 (1.8) | 1.00 |
| Atrial Fibrillation, n (%) | 11 (10.9) | 2 (3.6) | 0.14 |
| Hypercholesterolaemia, n (%) | 68 (64.8) | 27 (49.1) | 0.064 |
| NYHA ≥ II | 79 (71.8) | 6 (11.5) | <0.0001 |
Top panel comparison between mild/moderate and severe patients with aortic stenosis. Bottom panel comparison between all patients with aortic stenosis and controls. NYHA = New York Heart Association classification.