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. Author manuscript; available in PMC: 2017 Jul 13.
Published in final edited form as: J Am Chem Soc. 2017 May 8;139(19):6621–6628. doi: 10.1021/jacs.7b00617

Figure 2.

Figure 2

M2TM dynamics triggered by a laser-induced pH jump. (a) Time-dependent Trp fluorescence emission signal of a solution containing NPE-sulfate (0.8 mM) and M2TM reconstituted in a DPPC bicelle following a pH jump from pH 8.0 to 6.0, initiated with a 355 nm laser pulse. The data represent an average of 10 laser shots and were fit to a double exponential decay (red curve). (b) Dependence of the rate constant k1 of M2TM as a function of Δ[H+] at 25 °C. The red line is a linear fit to the data. (c) Schematic representation of the proton transfer pathway and proton channel activation process.