. Author manuscript; available in PMC: 2017 Jul 13.

Published in final edited form as: J Atheroscler Thromb. 2015 Mar 5;22(8):833–844. doi: 10.5551/jat.27292

Table 2.

Cardiac parameters assessed using transthoracic echocardiography

	WT				T1r4^lps-d
	Control	AngII	AngII + IRB	NE	Control	AngII	AngII + IRB	NE
LVEDd, ×10⁻¹ mm	43.2±0.3	42.3±0.5	39.0±1.2	40.8±0.9	39.3±0.8	40.5±0.9	39.3±0.7	41.8±0.9
LVESd, ×10⁻¹ mm	22.8±0.7	27.8±0.5^*	22.8±0.9	24.4±0.8	22.8±0.5	22.8±0.5	23.3±0.3	24.8±0.5
IVSWT, ×10⁻¹ mm	5.5±0.3	9.7±0.3^*	6.3±0.3	6.8±0.3	5.3±0.3	5.8±0.3	6.0±0.0	6.3±0.3
PWT, ×10⁻¹ mm	5.0±0.0	9.0±0.6^*	7.0±0.6	7.3±0.0	5.0±0.0	6.0±0.0	6.0±0.0	7.0±0.0
%FS, %	50.6±2.7	33.6±1.2^*	41.7±1.1	41.0±1.5	43.3±1.7	44.0±1.1	44.2±3.0	40.6±0.3
E/A ratio	2.4±0.2	1.4±0.7^*	1.9±0.8	2.0±0.1	2.3±0.2	2.1±0.1	2.3±0.2	2.0±0.1

The values are presented as the mean±SE. Each group, n = 3.

p<0.05 vs. the other groups.

WT, wild-type mice; T1r4^lps-d , TLR4-deficient mice; AngII, angiotensin II; NE, norepinephrine; IRB, irbesartan; LVEDd, left ventricular end-diastolic dimension; LVESd, left ventricular end-systolic dimension; IVSWT, interventricular septal wall thickness at end-diastole; PWT, posterior wall thickness at end-diastole; %FS, fractional shortening; E/A ratio, early ventricular filling wave (E wave)/late filling wave caused by atrial contractions (A wave) assessed on Echo Doppler.