TABLE 1:
Results of Sec23b+/− CreErT(+) x Sec23b+/fl matings to generate mice with tamoxifen-inducible, acinar cell–specific deletion of Sec23b.
| Genotype | Sec23b+/+ CreErT(+) | Sec23b+/+ CreErT(–) | Sec23b+/fl CreErT(+) | Sec23b+/fl CreErT(−) | Sec23b+/− CreErT(+) | Sec23b+/− CreErT(–) | Sec23b−/fl CreErT(+) | Sec23b−/fl CreErT(–) | p valuea |
|---|---|---|---|---|---|---|---|---|---|
| Expected ratio (%) | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 | 12.5 | |
| Percentage observed at weaning (n = 174) | 9 (16) | 13 (23) | 14 (24) | 14 (24) | 13 (22) | 13 (23) | 11 (19) | 13 (23) | >0.8 |
ap calculated for Sec23b−/fl CreErT(+) mice versus all other genotypes.