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. 2017 Feb 12;9(6):1477–1536. doi: 10.18632/aging.101250

Figure 11. Effects of berberine on TP53, miRs, apoptosis and drug resistance.

Figure 11

Berberine can induce the expression of TP53 and miRs which can alter the expression of many genes involved in the regulation of apoptosis, cell cycle progression and drug resistance. miRs which are oncomirs are indicated in maroon, miRs which are tumor suppressor miRs are indicated in blue.