. Author manuscript; available in PMC: 2018 Jul 1.

Published in final edited form as: Genesis. 2017 Jun 22;55(7):10.1002/dvg.23038. doi: 10.1002/dvg.23038

Table 2.

EIIa-Cre mediated recombination of Irf6^fl

tg ^EIIa-Cre/+ ; Irf6^gt/+ x tg^+/+ ; Irf6^gt/fl
Ella-Cre genotype	total	Irf6 genotype	total
tg^+/+	46	Irf6^fl	18
		Irf6^fl and Irf6^nl	0
		Irf6^nl	0
tg^EIIa/+	66	Irf6^fl	19
		Irf6^fl and Irf6^nl	8
		Irf6^nl	9

Data represent offspring from 15 litters collected at E17.5. Mice lacking the Ella-Cre transgene showed no recombination of the Irf6^fl allele. Mice carrying the Ella-Cre transgene showed mosaic recombination of Irf6^fl. Some offspring showed no recombination (Irf6^fl only), presence of both the Irf6^fl and Irf6^nl alleles, or complete recombination (Irf6^nl only).