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. Author manuscript; available in PMC: 2018 Mar 9.
Published before final editing as: Arch Pathol Lab Med. 2016 Sep 9:10.5858/arpa.2016-0156-RA. doi: 10.5858/arpa.2016-0156-RA

Figure 1.

Figure 1

Schematic representation of the “typical” pathology process in which multiple small tissue fragments are embedded in a single paraffin block. Facing of the block to adequately examine representative cross-sections of all tissue fragments can lead to waste of tissue that could otherwise be used for molecular and ancillary studies, as visualization of 1 fragment of tissue may require substantially cutting into another fragment(s) in the same block. Abbreviation: IHC, immunohistochemistry. Reprinted with permission from the Regents of the University of Colorado. Copyright 2016.