Figure 2.

Schematic representation of the approach used for our “molecular priority” specimen processing, in which tissue fragments are separately embedded and superficially faced. Superficial facing may result in nonvisualization of the complete tissue cross-section (represented by dotted line); however, as the goal is to evaluate for presence of tumor, superficial facing is often sufficient for this purpose. Abbreviations: FISH, fluorescence in situ hybridization; IHC, immunohistochemistry. Reprinted with permission from the Regents of the University of Colorado. Copyright 2016.