Figure 3.

When separate blocks are generated for separate tissue fragments, individual fragments can be chosen by best appropriateness for individual testing. Two separate blocks from the same biopsy procedure (A and C), with (B) and (D) demonstrating high-power images. On the basis of tumor content, the block shown in (A) was directed for fluorescence in situ hybridization analysis, and the remainder preserved for immunohistochemistry, and the block shown in (C) was directed for microdissection and mutation testing (original magnifications ×40 [A and C] and ×200 [B and D]).