Genes in the Screen Are Largely Representative of the Genome, Related to Figure 1 and Table S2
(A and B) Genes for which targeting vectors could be generated were similar (A) in size and (B) in A+T nucleotide content.
(C) Targeted genes had expression levels representative of the genome across all life stages (RPKM data from Otto et al., 2014).
(D) Relative representation of GO terms and multigene families in the genome and and the screen. The screen was largely representative with the exception of the P. berghei pir family (BIR) which we suspect is underrepresented due to its subtelomeric genomic location and repetitive nature. However, the well represented FAM family is shown for comparison.