Figure 3.

DAT blockade differentially affects dopamine release in ALDH1A1–positive and negative axons at DLS of control and mutant mice. (a) Percentages of electrical evoked dopamine amplitude (left) and uptake time constant (right) normalized to their baseline values (n = 5 animals per genotype, 2 sections per animal). Data were presented as mean ± SEM. Two-way ANOVA was used for statistical analysis, followed by Bonferroni’s post hoc tests. (b) Representative traces of electrically evoked dopamine release in DLS sub-compartments of control, Aldh1a1 ^−/− and α-synuclein A53T mutant mice, with CV curve as inset.