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. 2017 Jul 13;7:5316. doi: 10.1038/s41598-017-05493-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Flowchart of the PNS simulation process. Step 1: Preparation of the body model and nerve atlas (only required once). Step 2: EM fields imposed by the coil are calculated. Step 3: The electric field for a given coil current waveform is interpolated and projected onto the nerve fiber. Step 4: Nerves response is calculated to determine if an AP has been initiated. If no AP is reached, steps 3 and 4 are repeated with a higher amplitude coil current waveform until PNS is observed.