Table 1.

Statistically significant metabolites in all interactions.

Super Pathway	Sub Pathway	Biochemical Name	Fold Change
			TvDs/Tv	TvDs/Ds	TvPo/Tv	TvPo/Po	PoDs/Ds	PoDs/Po
Amino acid	Branched Chain Amino Acids (pyruvate derived)	2-methylbutyrylcarnitine (C5)	3.6	2.61	3.27	2.05	3.8	3.28
	Branched Chain Amino Acids (pyruvate derived)	isobutyrylcarnitine	14.57	4.6	12.13	1.82	7.93	3.76
	Branched Chain Amino Acids (pyruvate derived)	propionylcarnitine	2.64	3.91	5.24	2.05	9.73	2.58
	Aromatic amino acid metabolism (PEP derived)	tryptophan	6.29	11.04	8.18	119.94	8.58	71.73
Carbohydrate	Glycolysis	Isobar: hexose diphosphates	8.42	4.03	15.44	7.41	3.66	3.67
	Amino sugar and nucleotide sugar	N-acetylglucosamine	0.04	0.09	0.12	0.33	0.03	0.04
Cofactors, Prosthetic Groups, Electron Carriers	Carnitine metabolism	carnitine	4.09	1.6	3.36	2.1	1.65	2.63
	Oxidative phosphorylation	methylphosphate	6.8	5.92	4.41	4.67	2.85	3.47
	Nicotinate and nicotinamide metabolism	nicotinamide adenine dinucleotide (NAD+)	8.27	5.38	9.35	2.56	4.15	1.74
	Riboflavin and FAD metabolism	riboflavin (Vitamin B2)	3.99	2.88	2.41	2.07	2.24	2.67
Lipids	Glycerolipids	1-linoleoylglycerol (1-monolinolein)	5.39	5.39	5.38	2.85	4.97	2.63
	Phospholipids	1-linoleoylglycerophosphoethanolamine*	11.64	2.86	12.46	4.13	2.61	3.52
	Phospholipids	1-linoleoylglycerophosphoinositol*	16.2	3.35	14.45	8.93	2.58	7.7
	Glycerolipids	2-linoleoylglycerol (2-monolinolein)	5.7	9.52	4.26	5.8	5.23	4.25
	Carnitine metabolism	acetylcarnitine	1.47	2.5	2.28	2.29	3.27	1.93
	Phospholipids	glycerophosphorylcholine (GPC)	1.54	1.24	1.64	2.34	1.31	2.3
	Carnitine metabolism	hydroxybutyrylcarnitine*	3.91	2.19	4.2	2.78	3.25	3.84