Table 4.
Significant KEGG pathways corresponding to target union from miR-338 and miR-29b, with all of the Bonferroni, Benjamini and FDR values smaller than 0.05.
| Term | P-value | Bonferroni | Benjamini | FDR |
|---|---|---|---|---|
| hsa04510:Focal adhesion | 2.51 × 10−9 | 6.85 × 10−7 | 6.85 × 10−7 | 3.30 × 10−6 |
| hsa04110:Cell cycle | 1.60 × 10−7 | 4.36 × 10−5 | 2.18 × 10−5 | 2.10 × 10−4 |
| hsa05210:Colorectal cancer | 3.28 × 10−7 | 8.95 × 10−5 | 2.98 × 10−5 | 4.32 × 10−4 |
| hsa04151:PI3K-Akt signaling pathway | 7.05 × 10−7 | 1.92 × 10−4 | 4.81 × 10−5 | 9.28 × 10−4 |
| hsa05161:Hepatitis B | 5.94 × 10−6 | 1.62 × 10−3 | 3.24 × 10−4 | 7.83 × 10−3 |
| hsa05200:Pathways in cancer | 6.41 × 10−6 | 1.75 × 10−3 | 2.92 × 10−4 | 8.45 × 10−3 |
| hsa05166:HTLV-I infection | 1.38 × 10−5 | 3.76 × 10−3 | 5.37 × 10−4 | 1.82 × 10−2 |
| hsa05222:Small cell lung cancer | 1.96 × 10−5 | 5.34 × 10−3 | 6.69 × 10−4 | 2.58 × 10−2 |
| hsa04115:p53 signaling pathway* | 2.27 × 10−5 | 6.17 × 10−3 | 6.87 × 10−4 | 2.98 × 10−2 |
| hsa05215:Prostate cancer | 3.44 × 10−5 | 9.35 × 10−3 | 9.39 × 10−4 | 4.53 × 10−2 |
*Bold pathway corresponds to significant pathway which is insignificant using targets from either miR-338 or miR-29b.