Table 5.
Genes targeted by significant miRNA pairs in p53 signaling pathway.
| KEGG pathway | Genes targeted by either miR-210 or miR-30c | Genes targeted by either miR-338 or miR-29c | ||||||
|---|---|---|---|---|---|---|---|---|
| p53 signaling pathway | STEAP3 | CDK1 | CDK6* | RRM2B | CYCS | TP53 | CDK6* | SESN2 |
| PMAIP1 | CCNG1 | SESN3 | CCNB1* | SESN1 | PTEN | GTSE1 | ATM | |
| CCNE2 | CASP3 | CCND1* | CCND2* | CCNB1* | CCNE1 | PPM1D | CDKN1A | |
| RRM2 | SERPINE1 | DDB2 | MDM2* | CCND1* | CCND2* | BAX | CASP8 | |
| SIAH1* | FAS | THBS1* | IGFBP3 | MDM2* | SIAH1* | THBS1* | ||
*Bold genes represent the common genes targeted by both two significant miRNA pairs.