Table 5.
Profiles and responses of patients with metastatic pancreatic cancer in a HF10 phase I clinical trial.
| Patient | Age (years) | Clinical stage | HF10 PFU/0.5 mL/days | Time | Response | Survival (days) | Side effects | Shedding |
|---|---|---|---|---|---|---|---|---|
| 1 | 68 | Invasive ductal carcinoma | 1 × 105 × 3 | 1 | PD | 200 | None | No shedding into body fluids |
| 2 | 61 | 1 × 105 × 3 | 1 | SD | 166 | |||
| 3 | 60 | 5 × 105 × 3 | 3 | SD | 318 | |||
| 4 | 52 | 1 × 106 × 3 | 1 | PD | 98 | |||
| 5 | 73 | 1 × 106 × 3 | 3 | PR | 209 | |||
| 6 | 76 | 1 × 106 × 3 | 3 | SD | 315 | |||
| 7 | 49 | 1 × 106 × 6 | 6 | PD | 206 | |||
| 8 | 64 | 1 × 106 × 6 | 6 | PD | 113 |
PD, progressive disease; SD, stable disease; PR, partial response.