Figure 1.
UL36 inhibits apoptosis in Murine NIH3T3 cells. HEK293 (A) and NIH3T3 (B) cells were transfected with UL36 expressing vector and empty vector. Apoptosis was induced with CD95L 24 h post transfection and the cells were labeled with PE coupled anti-active caspase-3 1 day after stimulation with CD95L, this was followed by flow cytometric analysis. (*p < 0.05, Kruskall-Wallis test with Dunns post-analysis). (C) Representative contour plots of transfected cells pre-gated on mNeon. The gate shows the percentage of cells with active caspase-3.