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Cohesin shapes the centromere. a Model of the S. cerevisiae cohesin molecule. b Schematic representation of two S. cerevisiae sister chromosomes attached to the mitotic spindle showing how cohesin shapes the centromeres in yeast mitosis. Cohesin connects sister chromatids at chromosome arms but also links together centromeric chromatin, both by intrachromosome (blue) and interchromosome (purple) strand trapping, thereby forming a barrel-shaped structure underneath the kinetochore
