Table 6.
Change in health status after an inpatient pulmonary rehabilitation, for total group and each clinical phenotype
| All patients (N = 459) | Phenotype 1 (n = 27) moderate COPD–mild impact health status | Phenotype 2 (n = 271) moderate COPD–high impact health status | Phenotype 3 (n = 161) severe COPD–mild impact health status | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Before | End | p | Before | End | p | Before | End | p | Before | End | p | |
| Physiological functioning | ||||||||||||
| FEV1% of pred | 42.8 ± 17.9 | 43.9 ± 20.6 | 0.03 | 60.0 ± 18.6 | 63.7 ± 20.1 | 0.22 | 46.0 ± 18.3 | 47.2 ± 21.3 | 0.10 | 34.2 ± 12.1 | 34.8 ± 14.6 | 0.37 |
| BMI | 25.9 ± 5.4 | 25.1 ± 6.6 | <0.01 | 23.8 ± 3.8 | 24.0 ± 3.5 | 0.28 | 26.5 ± 6.0 | 25.3 ± 7.4 | <0.01 | 25.2 ± 4.3 | 24.8 ± 5.6 | 0.29 |
| VO2% of preda | 60.8 ± 19.0 | 64.9 ± 19.3 | <0.01 | 92.7 ± 12.0 | 90.1 ± 17.8 | 0.53 | 63.9 ± 16.0 | 67.7 ± 17.7 | 0.01 | 50.0 ± 14.0 | 55.8 ± 15.5 | <0.01 |
| Symptoms | ||||||||||||
| Subjective symptoms | 13.0 ± 3.8 | 9.8 ± 4.3 | <0.01 | 11.1 ± 3.9 | 7.7 ± 3.5 | 0.01 | 13.7 ± 3.6 | 10.4 ± 4.2 | <0.01 | 12.2 ± 4.0 | 9.1 ± 4.4 | <0.01 |
| Dyspnoea emotions | 12.9 ± 4.1 | 10.9 ± 4.0 | <0.01 | 10.5 ± 2.9 | 9.8 ± 3.9 | 0.29 | 13.9 ± 3.9 | 11.7 ± 4.1 | <0.01 | 11.6 ± 4.2 | 9.7 ± 3.6 | <0.01 |
| Fatigue | 41.8 ± 9.4 | 31.5 ± 10.6 | <0.01 | 37.9 ± 9.7 | 28.9 ± 9.2 | <0.01 | 45.7 ± 7.3 | 34.0 ± 9.9 | <0.01 | 35.9 ± 9.3 | 27.8 ± 10.7 | <0.01 |
| Functional impairment | ||||||||||||
| Subjective impairment | 16.5 ± 5.2 | 13.0 ± 5.2 | <0.01 | 13.3 ± 5.6 | 9.7 ± 4.1 | <0.01 | 17.7 ± 4.9 | 13.9 ± 5.0 | <0.01 | 14.9 ± 5.2 | 11.9 ± 5.1 | <0.01 |
| Behavioural impairment | 27.4 ± 14.2 | 25.3 ± 14.5 | <0.01 | 11.8 ± 6.4 | 11.9 ± 9.4 | 0.95 | 32.4 ± 14.3 | 28.4 ± 14.6 | <0.01 | 21.4 ± 10.5 | 22.4 ± 13.2 | 0.35 |
| Quality of life | ||||||||||||
| General QoL | 26.8 ± 14.8 | 19.5 ± 12.5 | <0.01 | 13.4 ± 7.1 | 12.3 ± 11.5 | 0.64 | 34.3 ± 13.6 | 22.9 ± 13.0 | <0.01 | 16.5 ± 8.6 | 14.9 ± 9.6 | 0.05 |
| HrQoL | 5.8 ± 1.7 | 4.1 ± 1.7 | <0.01 | 4.7 ± 1.5 | 3.4 ± 1.8 | 0.01 | 6.4 ± 1.5 | 4.3 ± 1.7 | <0.01 | 5.1 ± 1.5 | 3.8 ± 1.6 | <0.01 |
| Satisfaction relations | 3.9 ± 1.8 | 3.3 ± 1.7 | <0.01 | 3.4 ± 1.9 | 3.1 ± 1.7 | 0.56 | 4.3 ± 1.9 | 3.5 ± 1.7 | <0.01 | 3.1 ± 1.5 | 3.1 ± 1.6 | 0.82 |
Data are represented as mean ± SD, p values in bold: significantly different before and end rehabilitation (paired t test, p < 0.01
FEV 1 % forced expiratory volume in 1 s, BMI body mass index, VO 2 max maximal oxygen uptake, QoL quality of life, HrQoL health-related quality of life
aOne hundred fifty-one patients performed a maximal cycle ergometry test at the end of the rehabilitation (respectively, 13/77/61 patients per phenotype); the other patients performed an endurance cycle ergometry (data not shown)