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. 2017 Jul 14;8:336. doi: 10.3389/fneur.2017.00336

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Copyright © 2017 Teicher, De Col and Messlinger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activity of units displayed at 10-min (A) or 1-min intervals (B) normalized to the respective vehicle intervals, and changes after medullary administration of sodium sulfide (Na₂S). (A) The whole sample of 11 units showed no significant change in activity after local administration of Na₂S onto the spinal medulla. When each single unit was evaluated separately (one-way ANOVA at minute intervals), the neuronal activity of six units was increasing after Na₂S but not after vehicle administration. (B) Higher resolution revealed increased activity (*) in the group of activated units in minutes 5–7 after starting Na₂S administration compared to the 10-min interval before Na₂S infusion (ANOVA with repeated measures).