Fig. 4.

Dopamine neurons cell count. Mice brains were stained with anti-TH at 15 months. The total number of TH-positive cells from eight evenly spaced frozen sections that encompassed the entire SN of wt (n = 11), casp1^−/− (n = 7), and IL-1ra^−/− (n = 7) mice was evaluated from the unilateral side of SNpc. Data were analyzed by one-way ANOVA (Newman-Keuls post hoc test). Error bars represent standard errors. **P < 0.01 vs. wt; ⁺⁺ P < 0.01 vs. casp1^−/−