Table 4.

Distribution of the patient-reported symptoms associated with chordoma by treatment received

Symptom		All (n = 322) (%)	Treatment received					P-valuea
			Surgery only (n = 87) (%)	Radiotherapy only (n = 22) (%)	Medical therapy only (n = 3) (%)	No treatment (n = 8) (%)	Multiple therapy (n = 202) (%)
Chronic pain	(n = 122)	38	49	27	33	38	34	0.107
Depression or severe anxiety	(n = 111)	34	38	27	67	38	33	0.632
Chronic fatigue	(n = 106)	33	29	18	33	38	36	0.375
Difficulty walking	(n = 97)	30	34	27	33	50	28	0.502
Balance impairment	(n = 92)	29	22	23	33	38	32	0.394
Difficulty sitting	(n = 82)	25	44	18	33	50	17	0.001
Double vision	(n = 75)	23	13	32	33	25	27	0.046
Sexual dysfunction	(n = 72)	22	26	27	33	13	20	0.607
Limited mobility	(n = 62)	19	26	5	67	25	17	0.020
Urinary incontinence	(n = 49)	15	15	9	67	38	14	0.059
Urinary retention	(n = 46)	14	16	0	33	38	14	0.040
Chronic sinus problems	(n = 45)	14	5	18	0	13	18	0.022
Hearing loss	(n = 44)	14	6	18	33	13	16	0.050
Fecal incontinence	(n = 40)	12	18	14	33	13	9	0.128
Bowel obstruction	(n = 38)	12	15	9	67	13	10	0.075
Other vision problems	(n = 25)	8	3	14	33	13	8	0.084

Symptoms were asked using the following survey question: “Which of the following health effects have you (the patient) ever suffered as a result of chordoma?”

^a P-values were calculated using Fisher’s exact test