Figure 6. Effect of CO₂ on firing activity of Phox2b‐expressing neurons.

A, representative cell‐attached recording of firing rate in response to changes in different concentrations of CO₂ from a Phox2b‐expressing neurons in slices. Traces and histograms show a sustained increase in firing rate during 8% CO₂ bubbled bath solution (∼pH 7.1). B and C, average firing rate during changes in pH produced by altering CO₂ concentrations in neurons with sustained (B) (n = 6) and transient (C) (n = 4) responses. ^* P < 0.05 by a two‐tailed paired t test.