Skip to main content
. 2017 Jul 14;8:828. doi: 10.3389/fimmu.2017.00828

Table 2.

Macrophage reprogramming after WBI.

Reference Dose Radiation type Effect Model
(113) 0.2 and 2 Gy γ-ray M1 polarization WBI (without tumor)
(117) 0.075 and 2 Gy X-ray M1 polarization WBI (without tumor)
(114) 0.5–6 Gy X-ray M1 polarization WBI (without tumor)
(118) 0.01–0.02–0.1 Gy × 10/day × 2 weeks (LDI) X-ray Increased cytotoxic activity and nitric oxide Macrophages from BALB (L1)/c and C57BL/6 (Lewis lung cancer) mice (WBI)
(96) 0.5–2 Gy × 1 (MDI) X-ray M1 polarization Mouse RT5 insulinoma/Human MeWo melanoma xenograft/Human pancreas
(33) 2 Gy × 2 (MDI) γ-ray M1 polarization Rip1 Tag5 tumor-bearing mouse (WBI)

Green shading means M1 polarization. WBI, whole-body irradiation.