Binding site of
BsHPF‐NTD (green) and dimeric
BsHPF‐CTD (red, blue) relative to (C) RMF (orange; Polikanov
et al,
2012) and (D) SD–anti‐SD helix (yellow‐purple surface; Sohmen
et al,
2015). The dashed line indicates the linker and is shown only to illustrate that the 34 amino acids are more than sufficient to connect the NTD and CTD; however, no density for the linker was observed, suggesting it does not adopt a defined conformation on the ribosome.