Table 3.
STELLA subpopulations identified by gene product localization
| XPS/ACD | STELLA/OCT/PRDM11 STELLA/(OCT)/(PRDM1)/T2 |
| aPVE | STELLA/OCT/PRDM11 STELLA/OCT |
| Hindgut Lip/ Hindgut | STELLA/OCT/PRDM11 STELLA/OCT STELLA/OCT/FOXa23 STELLA/OCT/Runx1 |
| Other possible, but not yet proven, combinations4 | STELLA/OCT/PRDM1/Runx1 STELLA/OCT/FOXa2/PRDM1 STELLA/OCT-3/4/FOXa2/Runx1 STELLA/OCT-3/4/FOXa2/PRDM1/Runx1 |
Together with data in this study, we conclude that a STELLA/OCT/PRDM1 population is found in all putative PGC tissues (Mikedis and Downs, 2017).
STELLA invariably co-localized with PRDM1 in the allantoic component of the primitive streak (Mikedis and Downs, 2017) and co-localized in this study with T in just 3 cells in one late headfold-stage specimen.
STELLA/OCT/Foxa2 were found only in the hindgut lip, and not within the hindgut itself in this study.
These possible combinations are based on results here combined with those of previous studies (Mikedis and Downs, 2012, 2017).