Table 1.

Summary of Clinical Trials evaluating the relationship between mediterranean Diet and its components with erectile dysfunction

Study	Patient population	Design	Primary endpoint	Results
MЀDITA trial (MEditerranean DIet and Type 2 diAbetes) [5, 7]	106 male diabetic patients	Single center, randomized, controlled trial	Changes of IIEF after a total follow-up of 8.1 years in MedDiet (n = 54) or a low-fat diet (n = 52, control group).	Reduction in IIEF was significantly greater in the low-fat group compared to MedDiet (p = 0.024).
CAPRI (CAmpanian post-PrandIal hyperglycemia group) [6]	555 male diabetic patients	Large observational study	Prevalence and severity of ED according to MedDiet adherence by tertile of MedDiet score.	ED prevalence and severity in the highest tertile of adherence to MedDiet were significantly lower than in those with low adherence (p = 0.01).
Ramirez et al. [9]	440 male non diabetic patients	multicentre, observational, cross-sectional study	Prevalence of ED in a MedDiet cohort (No ED 254 patients, mild ED 109 patients, moderate severe ED 77 patients)	Consumptions of Nuts and vegetables were inversely related to ED
Wang et al. [8]	1466 male diabetic patients	Canadian Community Health Survey (CCHS)	Association between fruit/vegetable consumption and ED among Canadian men with diabetes.	The consumption of fruits and vegetables were inversely associated with ED.